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- Calcium-Oxalate Kidney
Stone Disease
 Links
The prevalence of urolithiasis,
or kidney stones, is epidemic in many parts of the world, leading
to demarcation of clearcut stone belt regions and pockets, one
of which is the southern USA. Despite many advances in the treatment
of urolithiasis, kidney stones remain a significant medical problem
with an incidence in the general population of 6-10% and a rising
incidence in various parts of the world. Once a kidney stone
is formed, it causes a permanent damage to renal tissue. Lithotripsy
or surgical removal no doubt adds to renal damage, plus there
is a high recurrence rate in stone-forming patients. Urolithiasis,
therefore, is a common cause of end-stage renal failure. Studies
have suggested a tenuous familial pattern, suggesting a genetic
contribution to being at risk for kidney stone formation. Urinary
stones are usually classified according to their composition
with the most frequently encountered being pure calcium oxalate
or calcium oxalate plus phosphate and/or urate. Although precipitation
of calcium oxalate is dependent on the supersaturation levels
of both calcium and oxalate ions in a metastable state, we believe
that oxalate ion concentration may be the more significant factor
in the formation of calcium oxalate kidney stones and that mild
hyperoxaluria is a major risk factor of calculogenesis.
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- Links:
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- Academic
- UCLA Kidney Stone
Treatment Center
The Kidney Stone Web Site
Kidney Stones - Publication
- The Beans - Assembly
of Kidney Disease Related Sites
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- Government
- Kidney Stones In
Adults
- Kidney Stones, Prescription
For Healing
- Urology - Associates / Societies / Foundations
- Health Care Information
Resources
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- Commercial
- The Worldwide Kidney Disease Community
- Houston Urology - Kidney
- Scanning Electron Micrographs of Kidney
Stones
- Dead Doctors - Kidney Disease
- Nephrology Resources
- Australian Kidney Foundation - International
Links
- Resource Central - Disease & Illnesses
Resources
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