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Scientific Articles

Ixion encourages its scientists to publish in peer reviewed scientific journals. We adopted this policy for two reasons:

FIRST...

we needed to recruit academic scientists who regard publication of scientific results as important;
SECOND...

because our technologies tend to be very cutting edge, they generally have not benefited from wide-spread scientific acceptance, which is partly overcome by publication in reputable journals.

We intend to continue this policy by encouraging new employees to publish. Ixion Authors, Articles, and Presentations are listed below.

Manuscripts published
relating to oxalate technology

Click here to go to the beginning of
"Published manuscripts, abstracts, and reprints relating to stem cells"

  • Sidhu, H., Allison, M., and Peck, A. B. Identification and classification of Oxalobacter formigenes strains by using oligonucleotide probes and primers. J. Clin. Micro. 35: 350-353, 1997.

  • Sidhu, H., Ogden, S.D., Lung, H.Y., Luttge, B.G., Baetz, A.L., and Peck, A.B. DNA sequencing and expression of the formyl-CoA transferase gene, frc, from Oxalobacter formigenes. J. Bact. 179: 3378-3381, 1097.

  • Sidhu, H., Enatska, L., Ogden, S., Williams, W.N., Allison, M.J., and Peck, A.B. Natural colonization of children in the Ukraine with the intestinal bacterium, Oxalobacter formigenes, using a PCR_based detection system. Mol. Diag., 2: 89-97, 1997.

  • Sidhu, H., Hoppe, B., Hesse, A., Tenbrock, K., Bromme, S., Rietschel, E., and Peck, A.B. Absence of Oxalobacter formigenes in cystic fibrosis patients: a risk factor for hyperoxaluna. Lancet, 352: 1026-1029, 1998.

  • Sidhu, H., Holmes, R., Allison, M.J. and Peck, A.B. Direct quantification of the enteric bacterium, Oxalobacter formigenes, in human fecal samples using quantitative competitive template PCR. J. Clin. Micro., 37:1503-1509, 1999.

  • Sidhu H., Schmidt, M., Cornelius J., Thamilselvan, S., Khan, S., Hesse, A., and Peck, A.B. Direct correlation between hyperoxaluria/oxalate stone disease and the absence of the gastrointestinal tract dwelling bacterium O.formigenes: Possible prevention by gut recolonization or enzyme replacement therapy. J. Am.Soc. Neph., 10: S334-340, 1999 (Supplement 14).

  • Sidhu H. and A.B. Peck, Controlling plasma/urinary oxalate levels with a little help from our friends Oxalobacter formigenes. Nephrol. Dialysis. Transplant, 14:2787, 1999.

  • Neuhaus, T.J., Belzer T., Blau, N., Hoppe, B., Sidhu, H. and E. Leumann, Urinary oxalate excretion in urolithiais and nephrocalcinosis. Arch. Dis. Child, 82, 322-326, 2000.

  • Sidhu, H., Hoppe, B., Hesse, A., Bhandari, M., Cave, D.R. and Peck, A.B. Clinical significance of Oxalobacter formigenes: colonization studies in patients of cystic fibrosis, inflammatory bowel disease and calcium oxalate urolithiasis. Urolithiasis 2000, Vol-2, (Proceedings of the 9th International Symposium of Urolithiasis), 468-473, 2000.

  • Sidhu, H., Allison, M.J., Chow, J-M, Clark, A. and Peck, A. B. Rapid reversal of hyperoxaluria in a rat model following probiotic administration of Oxalobacter formigenes. J. Urol., 166, 1487-1491, 2001.

  • Malpass, C., Millsap, K.W, Sidhu, H. and Gower, L. Immobilization of an oxalate-degrading enzyme on silicone elastomer. J. Biomed Mater Res (Appl. Biomater) 63: 822-829, 2002.

  • Kumar, R., Mukherjee, M., Bhandari, M., Kumar A., Sidhu, H. and Mittal RD. Role of Oxalobacter formigenes in calcium oxalate stone disease: a study from North India. Eur. Urol. 41, 318-322, 2002.

  • Troxel S.A., Sidhu, H., Kaul, P. and Low R.K. Intestinal Oxalobacter formigenes colonization in calcium oxalate stone formers and its relation to urinary oxalate. J. Endourol. 17, 173-176, 2003.

  • Watterson J.D., Cadieux PA, Beiko DT, Cook AJ, Burton JP, Harbottle RR, Lee c, Rowe E, Sidhu H, Reid G and Denstedt JD. Oxalate degrading enzymes from Oxalobacter formigenes: A novel device coating to reduce urinary tract biomaterial related encrustation. J. Endourol. 17, 269-274, 2003.


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    Published manuscripts, abstracts, and reprints relating to stem cells, including:

  • Yin, L.; Sun, M.; Ilic, Z.;, Leffert, H.L.:, and Sell, S.: Derivation, characterization, and phenotypic variation of hepatic progenitor cell lines isolated from adult rats. Hepatology, 35: 315 (2002).

  • Yin, L.; Lynch, D.; Illic, Z.; and Sell, S.: Proliferation and differentiation of ductular progenitor cells and littoral cells during the regeneration of the rat liver to CCL4/2-AAF injury., Histol Histopathol., 17: 65 (2002).

  • Yin, L.; Arenas, M.S.; Clark, A.; Jodoin, E.; Zhou, J.; Lefferet, H.L., Sell, S.; Peck, A.B.; and Ramiya, V.K.: The potentiality of liver oval cells to differentiate into insulin-producing cells (abstract). NIDDK Workshop on Pancreatic Development, Proliferation, and Stem Cells, p 48. Bethesda, Maryland, October 18-19, 2001.

  • Zhou, J.; Clark, A.; Jodoin, E.; Arenas, M.S.; Yin, L.; Peck, A.B.; and Ramiya, V.K.: Differentiation of adult pancreatic ductal epithelial cells into cells expressing insulin cell markers in vitro (abstract). NIDDK Workshop on Pancreatic Development, Proliferation, and Stem Cells, p 45. Bethesda, Maryland, October 18-19, 2001.

  • Peck, A.B., Cornelius, J.G., Julius, M.C., Ramiya, V.K.: Growth and Differentiation of Islet Stem Cells to Functional Endocrine Pancreas (abstract). NIH Workshop on Stem Cells and Pancreatic Development, page 26, Bethesda, Maryland, April 10-11, 2000.

  • Ramiya, V.K., Maraist, M., Arfors, K-E., Schatz, D.A., Peck, A.B., Cornelius, J.G.: Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nature Medicine, 6: 278-282, 2000

  • Peck, A.B.; Nguyen, K.H-T; Brayer, J.; Cha, S.; Yasunari, U.; Nakashima, H.; Humphreys-Beher, M.G.: Salivary glad dysfunction in autoimmune NOD mice (abstract). NIH Workshop on Oral Diseases and Diabetes, Bethesda, Maryland, December 1999.

  • Robinson, C.P., Cornelius, J., Bounous, D. E., Yamamoto, H., Humphreys-Beher, M.G., Peck, A.B.: Characterization of the changing lymphocyte populations and cytokine expression in the exocrine tissues of autoimmune NOD mice. Autoimmunity, 27: 29-44, 1998

  • Peck, A.B., Cornelius, J.G.: Autocrine and paracrine growth factors elaborated during growth of islet-producing stem cells. IBC Conference Presentation, Boston, MA., May 1997

  • Cornelius, J.G., Tchernev, V., Kao, K.-J., Peck, A.B.: In vitro-generation of islets in long-term cultures of pluripotent stem cells from adult mouse pancreas. Hormone & Metabolic Res., 29: 271-277, 1997.

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